HUMAN HEPATIC MICROBODIES WITH CRYSTALLOID CORES
نویسندگان
چکیده
منابع مشابه
Human Hepatic Microbodies with Crystalloid Cores
Hepatic microbodies were first described in 1956 by Rouiller and Bernhard (1) and by Gansler and Rouiller (2). In the rat, they are round or oval bodies that are somewhat smaller than mito-chondria. They are delimited by a unit membrane and possess a moderately dense matrix and a dense core or nucleoid with a distinctive crystalloid arrangement. Microbodies have been characterized biochemically...
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The liver of male rats has been studied after CPIB stimulation by using the peroxidase reaction for localizing catalase in hepatic cells. CPIB administration leads to an increase in the number of microbodies, and it is suggested that one mechanism by which microbody proliferation occurs is a process of fragmentation or budding from preexisting microbodies. Reaction product was observed not only...
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Prominent staining of rat hepatic microbodies was obtained by incubating sections of aldehyde-fixed rat liver in a modified Graham and Karnovsky's medium for ultrastructural demonstration of peroxidase activity. The electron-opaque reaction product was deposited uniformly over the matrix of the microbodies. The microbodies were identified by their size, shape, presence of tubular nucleoids, and...
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Microbodies were first reported at the ultrastructural level in the proximal convoluted tubule ofmouse kidney by Rhodin in 1954 (1) and in hepatic parenchymal cells by Rouiller and Bernhard in 1956 (2) at about the time The Journal of Cell Biology was established . They were reported in plants by Porter and Caulfield in 1958 (3) and by Mollenhauer et al. in 1966 (4) . Microbodies are now recogn...
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SUMMARY The structure of microbodies, when present, and the activities of three microbody enzymes (catalase, urate oxidase, and D-amino acid oxidase) were studied in 35 transplantable hepatomas. Microbodies are absent in hepatomas 3683, 7794A, and BRL-4-C-3. The number, size, and often the internal structures of microbodies in the other hepatomas generally reflect the growth rates and, to a cer...
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ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 1966
ISSN: 1540-8140,0021-9525
DOI: 10.1083/jcb.29.2.383